Epigenetic Deregulation of Apoptosis in Cancers
نویسندگان
چکیده
منابع مشابه
Mechanisms of epigenetic deregulation in lymphoid neoplasms.
Aberrant lymphoma epigenome is the result of a combinatorial contribution of changes in DNA methylation, histone modifications, and noncoding RNA (ncRNA) expression in lymphoma cells. All of the components of epigenome have been the focus of intense studies in various subtypes of lymphoma, which resulted in the deeper understanding of novel mechanisms of lymphomagenesis and revealed novel thera...
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Apoptosis, or programmed cell death, is central to the development and homeostasis of the hematopoietic system. Dysregulation of apoptosis plays an important role in the development of a variety of human pathologies, including cancer, autoimmune diseases and neurodegenerative disorders. Particularly, studies carried out in the last years have shown that leukemia cells invariably have abnormalit...
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ژورنال
عنوان ژورنال: Cancers
سال: 2021
ISSN: 2072-6694
DOI: 10.3390/cancers13133210